Effects of a prescribed supervised exercise program on mortality and cardiovascular morbidity in patients after a myocardial infarction: The National Exercise and Heart Disease Project

Publication Description
This study enrolled 651 men with myocardial infarction in five participating centers in a randomized 3 year clinical trial of the effects of prescribed supervised exercise. The subjects, aged to 30 to 64 years, were screened for eligibility 2 to 36 months after their qualifying myocardial infarction. The men in the exercise group pursued intensive exercise in the laboratory for 8 weeks and then in a gymnasium for 34 months. The experience of the exercise group was more favorable than that of the control group in most of the comparisons made. The cumulative 3 year total mortality rate was 7.3 percent for the control group and 4.6 percent for the exercise group; the 3 year rate for recurrent myocardial infarction was 7.0 and 5.3 percent, respectively. Mortality rates in the two groups did not differ significantly, but the data were consistent with an assumption of substantial benefit from exercise. Adjustment for small differences in baseline variables by multivariate methods did not materially alter the estimate of effect of exercise. Certain subgroups showed a greater benefit from exercise.

Primary Author
Shaw,Lawrence
Shaw,Lawrence W.
Oberman,Albert
Barnes,Glenda
Eggert,Del
Barton,Stephen N.
Hellerstein,Herman
Insua,Jorge
Yoran,Chaim
Fardy,Paul
Franklin,Barry A.
Gilbert,Charles
Blessing,Daniel Lee
Johnson,Barbara
Gorman,Patrick
LaVelle,Margie
Everett,Marcia
Barry,Alan
Daly,James
Satinsky,John
Marley,William
Cleary,Patricia
Rios,Jorge
Stern,Melvin
Paup,Donald
Bogarty,Dan
Kavanaugh,Patricia
Schlesselman,Sarah
LaRosa,John
Naughton,John
Moriarity,Barbara E.

Volume
48

Issue
1

Start Page
39

Other Pages
46

Publisher
Elsevier Inc

URL
https://www.sciencedirect.com/science/article/pii/0002914981905701

PMID
6972693



Reference Type
Journal Article

Periodical Full
The American Journal of Cardiology

Publication Year
1981

Place of Publication
United States

ISSN/ISBN
0002-9149

Document Object Index
10.1016/0002-9149(81)90570-1