Background: Recruitment of participants into research studies, especially individuals from minority groups, is challenging; lack of diversity may lead to biased findings. Aim: To explore beliefs about research participation among individuals who were approached and eligible for the GRADE study (Glycemia Reduction Approaches in Diabetes, A Comparative Effectiveness Study). Methods: In-depth qualitative telephone interviews with randomized participants (n = 25) and eligible individuals who declined to enroll (n = 26). Results: Refusers and consenters differed in trust and perceptions of risk, benefits and burden of participation. Few participants understood how comparative effectiveness research differed from other types of trials; however, some features of comparative effectiveness research were perceived as lower risk. Conclusion: We identified facilitators and addressable barriers to participation in research studies.; Background: Recruitment of participants into research studies, especially individuals from minority groups, is challenging; lack of diversity may lead to biased findings. Aim: To explore beliefs about research participation among individuals who were approached and eligible for the GRADE study (Glycemia Reduction Approaches in Diabetes, A Comparative Effectiveness Study). Methods: In-depth qualitative telephone interviews with randomized participants (n = 25) and eligible individuals who declined to enroll (n = 26). Results: Refusers and consenters differed in trust and perceptions of risk, benefits and burden of participation. Few participants understood how comparative effectiveness research differed from other types of trials; however, some features of comparative effectiveness research were perceived as lower risk. Conclusion: We identified facilitators and addressable barriers to participation in research studies.
Reference Type
Generic
Periodical Full
Journal of Comparative Effectiveness Research
Publication Year
2019
Publication Date
08/01/
Volume
8
Issue
10
Start Page
815
Other Pages
826
Publisher
Future Medicine
ISSN/ISBN
2042-6305
Document Object Index
10.2217/cer-2019-0010
URL
https://doi.org/10.2217/cer-2019-0010
PMID
31368793
PMCID
PMC7333580