Publication Description
BACKGROUND: Short cervix at mid-gestation, the presence of intra-amniotic debris, and cervical funneling are risk factors for preterm birth (PTB), however cervic length (CL) measurements and cutoffs are not well documented among pregnant patients of different gestational ages (GA) and self-reported races and ethnicities. OBJECTIVE: To describe the distribution of CL, and frequency of funneling and debris, at mid-gestation in nulliparous women by gestational age (GA) and race/ethnicity. STUDY DESIGN: Secondary analysis of screening data from a multicenter treatment trial of singleton nulliparous patients with short cervix, conducted at 14 geographically distribued, university affiliated medical centers in the U.S. Singleton nulliparous patients with no known risk factors for PTB were screened for trial participation and asked to undergo a transvaginal ultrasound to measure CL by a certified sonographer. The distribution of CL and the frequency of funneling and debris, were assessed for each GA week (16 to 22 weeks) and stratified by self-reported race and ethnicity, which for this study were catgorized as White, Black, Hispanic and other. Patients enrolled in the randomized trial were excluded from this analysis. RESULTS: 12,407 nulliparous patients were included in this analysis. The racial/ethnic distribution of study participants was as follows: White 41.6%, Black 29.6%, Hispanic 24.2%, and others 4.6%. The 10th percentile CL for the entire cohort was 31.1 mm, and when stratified by race and ethnicity, 31.9 mm for White, 30.2 mm for Black, 31.4 mm for Hispanic, and 31.2 mm for patients of other race and ethnicity (p