Design, data monitoring, and analysis of clinical trials with co-primary endpoints: A review

We review the design, data monitoring, and analyses of clinical trials with co-primary endpoints. Recently developed methods for fixed-sample and group-sequential settings are described. Practical considerations are discussed, and guidance for the application of these methods is provided.

Primary Author

Hamasaki,Toshimitsu

Evans,Scott R.

Asakura,Koko

Volume

Issue

Start Page

Other Pages

Publisher

Taylor & Francis

URL

http://www.tandfonline.com/doi/abs/10.1080/10543406.2017.1378668

PMID

29083951

Reference Type

Journal Article

Periodical Full

Journal of biopharmaceutical statistics

Publication Year

2018

Publication Date

Jan 2,

Place of Publication

England

ISSN/ISBN

1054-3406

Document Object Index

10.1080/10543406.2017.1378668