Biostatistical Analysis of the Collaborative Glaucoma Study: I. Summary Report of the Risk Factors for Glaucomatous Visual-Field Defects

Publication Description
• A prospective collaborative study was conducted in five centers during a 13-year period to identify factors that influence the development of visual-field defects (GVFDs) of open angle glaucoma. In 5,000 subjects, GVFDs developed in only 1.7% of eyes. Statistical analysis of 26 factors at first examination identified five that were significantly related to the development of GVFDs—outflow facility, age, applanation pressure, cup-disc ratio, and pressure change after water drinking. Their absolute initial value, and not its change with time, was the important predictor. Multivariate analysis showed their collective predictive power to be undesirably poor, indicating that other factors must play an important role in the development of GVFDs. Mortality-table analysis indicated that during a period of five years, 98.54% of eyes with initial pressure less than 20 mm Hg continued to be free from GVFDs as compared with 93.34% of those with pressure 20 mm Hg or greater.

Primary Author
Armaly,Mansour F.
Krueger,Dean E.
Maunder,Lucinda
Becker,Bernard
Hetherington,John
Kolker,Allan E.
Levene,Ralph Z.
Maumenee,A. Edward
Pollack,Irvin P.
Shaffer,Robert N.

Volume
98

Issue
12

Start Page
2163

Other Pages
2171

Publisher
American Medical Association

URL
http://dx.doi.org/10.1001/archopht.1980.01020041015002

PMID
7447768



Reference Type
Journal Article

Periodical Full
Archives of Ophthalmology

Publication Year
1980

Publication Date
Dec 1,

Place of Publication
United States

ISSN/ISBN
0003-9950

Document Object Index
10.1001/archopht.1980.01020041015002