Changes in Visceral and Subcutaneous Fat in Youth With Type 2 Diabetes in the TODAY Study

In the Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) study, metformin plus rosiglitazone (M + R) maintained glycemic control better than metformin alone (M) or metformin plus lifestyle (M + L) in youth with type 2 diabetes (T2D). We hypothesized that changes in visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) would explain the differential treatment effects on glycemia. In 626 youth ages 11-17 years with T2D duration

Primary Author

Dhaliwal,Ruban

Shepherd,John A.

El Ghormli,Laure

Copeland,Kenneth C.

Geffner,Mitchell E.

Higgins,Janine

Levitsky,Lynne L.

Nadeau,Kristen J.

Weinstock,Ruth S.

White,Neil H.

Volume

Issue

Start Page

1549

Other Pages

1559

Publisher

American Diabetes Association

URL

https://www.ncbi.nlm.nih.gov/pubmed/31167889

PMID

31167889

Reference Type

Journal Article

Periodical Full

Diabetes care

Publication Year

2019

Publication Date

Aug

Place of Publication

United States

ISSN/ISBN

0149-5992

Document Object Index

10.2337/dc18-1935