Frequency of Evidence-Based Screening for Retinopathy in Type 1 Diabetes

Publication Description
The probability of progression from “preclinical” diabetic retinopathy to proliferative retinopathy or clinical macular edema was estimated. Individualized screening frequency based on the current retinopathy state and glycated hemoglobin level appeared to be feasible. Diabetic retinopathy is the most common cause of blindness in adults in the United States. 1 Fortunately, the risk of the development and progression of retinopathy can be reduced substantially by modern-day intensive glycemic management. 2 – 5 Moreover, if clinically significant macular edema or vision-threatening proliferative diabetic retinopathy develops, timely intervention with laser photocoagulation or with intraocular glucocorticoids or anti–vascular endothelial growth factor (VEGF) agents can substantially reduce loss of vision. 6 – 9 Thus, the goal of retinopathy screening is the timely detection of retinopathy that would, without intervention, cause vision loss. In patients with type 1 diabetes, annual screening for retinopathy starting . . .

Primary Author
Nathan,David M.
Bebu,Ionut
Hainsworth,Dean
Klein,Ronald
Tamborlane,William
Lorenzi,Gayle
Gubitosi-Klug,Rose
Lachin,John M.

Volume
376

Issue
16

Start Page
1507

Other Pages
1516

Publisher
Massachusetts Medical Society

URL
http://dx.doi.org/10.1056/NEJMoa1612836 http://dx.doi.org/10.1056/NEJMoa1612836



Reference Type
Journal Article

Periodical Full
The New England journal of medicine

Publication Year
2017

Publication Date
Apr 20,

Place of Publication
United States

ISSN/ISBN
0028-4793

Document Object Index
10.1056/NEJMoa1612836