Risk factors for orgasmic and concomitant erectile dysfunction in men with type 1 diabetes: a cross-sectional study

Publication Description
In this study, we sought to determine the burden and characteristics of orgasmic dysfunction (OD) and concomitant erectile dysfunction (ED) in men with type 1 diabetes (T1D) enrolled in the Epidemiology of Diabetes Interventions and Complications (EDIC) study. In 2010, we assessed orgasmic and erectile function using the International Index of Erectile Function (IIEF). Sociodemographic, clinical, and diabetes characteristics were compared by OD status (OD only, OD and ED, no ED or OD). Age-adjusted associations between risk factors and OD status were examined. OD and ED information was available from 563 men. Eighty-three men (14.7%) reported OD of whom 21 reported OD only and 62 reported OD and ED. Age-adjusted odds ratios demonstrated that men who reported OD only had higher odds of depression, low sexual desire, and decreased alcohol use compared with men reporting no dysfunction. Men with OD concomitant with ED had greater odds of elevated hemoglobin A1C, peripheral and autonomic neuropathy, and nephropathy. Men reporting both dysfunctions were also more likely to report smoking, lower urinary tract symptoms, and had greater odds of androgen deficiency than men with no sexual dysfunction. Men with longstanding T1D suffer from an increased burden of OD. Psychogenic factors predominate in men reporting OD only while men who present with concomitant ED report increased burden of diabetes severity, characteristics previously observed with incident ED. ED may be the central impediment to sexual function in men with OD and ED. Longitudinal studies to characterize OD and ED experience over time are warranted.

Primary Author
Agochukwu-Mmonu,Nnenaya
Malaeb,Bahaa S.
Hotaling,James M.
Braffett,Barbara H.
Holt,Sarah K.
Dunn,Rodney L.
Palmer,Melody R.
Martin,Catherine L.
Jacobson,Alan M.
Herman,William H.
Wessells,Hunter
Sarma,Aruna V.

Volume
33

Issue
1

Start Page
59

Other Pages
66

Publisher
Nature Publishing Group

URL
https://www.ncbi.nlm.nih.gov/pubmed/32157243 https://www.ncbi.nlm.nih.gov/pubmed/32157243



Reference Type
Journal Article

Periodical Full
International Journal of Impotence Research

Publication Year
2021

Publication Date
Jan

Place of Publication
England

ISSN/ISBN
0955-9930

Document Object Index
10.1038/s41443-020-0242-8